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Article

ROS signaling by NADPH oxidase 5 modulates the proliferation and survival of prostate carcinoma cells

5 Jan 2015

Abstract excerpt

Prostate cancer (PCa) is the most commonly diagnosed cancer and second leading cause of male cancer death in Western nations. Thus, new treatment modalities are urgently needed. Elevated production of reactive oxygen species (ROS) by NADPH oxidase (Nox) enzymes is implicated in tumorigenesis of the prostate and other tissues. However, the identity of the Nox enzyme(s) involved in prostate carcinogenesis remains...

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 25559363
DOI: 10.1002/mc.22255

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