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Article

Clinical significance of DNA methylation mRNA levels of TET family members in colorectal cancer

3 Jan 2015

Abstract excerpt

PURPOSE: Ten eleven translocation (TET) enzyme activity is essential for active DNA demethylation in biological processes, and their altered expression has been observed in various malignancies. Therefore, we investigated DNA methylation and mRNA levels of all TETs in colorectal cancer (CRC) patients. METHODS: TET mRNA levels were evaluated using quantitative RT-PCR in primary cancerous and histopathologically...

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PMID: 25557833
DOI: 10.1007/s00432-014-1901-2

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