Article
Genetic Variations in MicroRNA-Binding Sites Affect MicroRNA-Mediated Regulation of Several Genes Associated With Cardio-metabolic Phenotypes.
Circulation. Cardiovascular genetics - 1 Jun 2015
Ghanbari Mohsen, Franco Oscar H, de Looper Hans W J, Hofman Albert, Erkeland Stefan J, Dehghan Abbas
Abstract excerpt
BACKGROUND: Genome-wide association studies enabled us to discover a large number of variants and genomic loci contributing to cardiovascular and metabolic disorders. However, because the vast majority of the identified variants are thought to merely be proxies for other functional variants, the...
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