Article
Evidence for pelvic organ prolapse predisposition genes on chromosomes 10 and 17.
American journal of obstetrics and gynecology - 1 Jun 2015
Allen-Brady Kristina, Cannon-Albright Lisa A, Farnham James M, Norton Peggy A
Abstract excerpt
OBJECTIVE: We conducted a genomewide linkage analysis to identify pelvic organ prolapse (POP) predisposition genes using a resource of high-risk POP pedigrees. STUDY DESIGN: Cases are defined as women who reported bothersome symptoms of POP based on standardized symptom questions (Pelvic Floor Distress Inventory, moderately or quite bothered), and/or received treatment for POP documented in medical records. Our...
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