Article
The polymorphism of hypoxia-inducible factor-1a gene in endometrial cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Kafshdooz Leila, Tabrizi Ali Dastranj, Mohaddes Seyyed Mojtaba, Kafshdooz Tayebeh, Akbarzadeh Abolfazl, Ghojazadeh Morteza, Gharesouran Jalal
Abstract excerpt
BACKGROUND: Endometral carcinoma is the most common malignant tumor of the female genital tract and the fourth most common cancer in women after breast, colorectal and lung cancers Hypoxia-inducible factor -1 (HIF-1) is a key transcription factor that regulates cellular response to hypoxia HIF-1 plays important roles in the development and progression of cancer through activation of various genes that are...
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