Article
Hypoxia-inducible factor-1α C1772T polymorphism and cancer risk: a meta-analysis including 18,334 subjects.
Cancer investigation - 1 May 2014
Ye Yanwei, Wang Min, Hu Shuang, Shi Yingqiang, Zhang Xiefu, Zhou Ye, Zhao Chunlin, Wang Guojun, Wen Jianguo, Zong Hong
Abstract excerpt
Studies on HIF 1α C1772T (P582S) polymorphism revealed a genetic susceptibility to malignant tumors, however, the results were conflicting. We conducted a meta-analysis utilizing 29 eligible case-control studies to analyze the data concerning the association between the HIF-1α C1772T polymorphism and cancer risks. There was statistical association between the HIF-1α CT/TT genotype and cancer risk (OR = 1.28, 95%...
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