Article
Increased number of white matter lesions in patients with familial cerebral cavernous malformations.
AJNR. American journal of neuroradiology - 1 May 2015
Golden M J, Morrison L A, Kim H, Hart B L
Abstract excerpt
BACKGROUND AND PURPOSE: Familial cerebral cavernous malformations, an autosomal dominant disorder, result in excess morbidity and mortality in affected patients. The disorder is most prevalent in the Southwest United States, where the affected families are most often carriers of the CCM1-KRIT1 Co...
Topics
- Adolescent
- Brain
- Child
- Female
- Hemangioma, Cavernous, Central Nervous System
- Heterozygote
- Humans
- KRIT1 Protein
- Logistic Models
- Magnetic Resonance Imaging
- Male
- Microtubule-Associated Proteins
- Mutation
- Prevalence
- Proto-Oncogene Proteins
- Southwestern United States
- White Matter