Article
Association of cardiovascular risk factors with disease severity in cerebral cavernous malformation type 1 subjects with the common Hispanic mutation.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2014
Choquet Hélène, Nelson Jeffrey, Pawlikowska Ludmila, McCulloch Charles E, Akers Amy, Baca Beth, Khan Yasir, Hart Blaine, Morrison Leslie, Kim Helen
Abstract excerpt
BACKGROUND: Cerebral cavernous malformations (CCM) are enlarged vascular lesions affecting 0.1-0.5% of the population worldwide and causing hemorrhagic strokes, seizures, and neurological deficits. Familial CCM type 1 (CCM1) is an autosomal dominant disease caused by mutations in the Krev Interac...
Topics
- Adolescent
- Adult
- Age of Onset
- Body Mass Index
- Brain
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Child
- Cohort Studies
- Cross-Sectional Studies
- Female
- Genetic Predisposition to Disease
- Hemangioma, Cavernous, Central Nervous System