Article
Targeted therapy for hereditary cancer syndromes: hereditary breast and ovarian cancer syndrome, Lynch syndrome, familial adenomatous polyposis, and Li-Fraumeni syndrome.
Discovery medicine - 1 Dec 2014
Agarwal Rishi, Liebe Sarah, Turski Michelle L, Vidwans Smruti J, Janku Filip, Garrido-Laguna Ignacio, Munoz Javier, Schwab Richard, Rodon Jordi, Kurzrock Razelle, Subbiah Vivek
Abstract excerpt
Cancer genetics has rapidly evolved in the last two decades. Understanding and exploring the several genetic pathways in the cancer cell is the foundation of targeted therapy. Several genomic aberrations have been identified and their role in carcinogenesis is being explored. In contrast to most...
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