Article
Systemic Treatment Strategies for Patients with Hereditary Breast Cancer Syndromes.
The oncologist - 1 Jun 2017
Parkes Amanda, Arun Banu K, Litton Jennifer K
Abstract excerpt
Hereditary breast cancer syndromes are associated with an increased risk of breast cancer and constitute a unique patient population, making up approximately 5%-10% of breast cancer cases in the United States. By virtue of the germline mutations that define these syndromes, invasive breast cancers in these patients have unique mechanisms that can be rationally targeted for therapeutic opportunities distinct from...
Topics
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Germ-Line Mutation
- Humans
- Mutation
- Neoplastic Syndromes, Hereditary
- United States