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Article

Citrate synthase expression affects tumor phenotype and drug resistance in human ovarian carcinoma.

PloS one - 1 Jan 2014

Chen Lilan, Liu Ting, Zhou Jinhua, Wang Yunfei, Wang Xinran, Di Wen, Zhang Shu

Abstract excerpt

Citrate synthase (CS), one of the key enzymes in the tricarboxylic acid (TCA) cycle, catalyzes the reaction between oxaloacetic acid and acetyl coenzyme A to generate citrate. Increased CS has been observed in pancreatic cancer. In this study, we found higher CS expression in malignant ovarian tu...

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Source

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Identifiers

PMID: 25545012
DOI: 10.1371/journal.pone.0115708
PMCID: PMC4278743

Genes

CASP7
ERCC1
ISG15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25545012-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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