Article
Genomic investigation of etiologic heterogeneity: methodologic challenges.
BMC medical research methodology - 22 Dec 2014
Begg Colin B, Seshan Venkatraman E, Zabor Emily C, Furberg Helena, Arora Arshi, Shen Ronglai, Maranchie Jodi K, Nielsen Matthew E, Rathmell W Kimryn, Signoretti Sabina, Tamboli Pheroze, Karam Jose A, Choueiri Toni K, Hakimi A Ari, Hsieh James J
Abstract excerpt
BACKGROUND: The etiologic heterogeneity of cancer has traditionally been investigated by comparing risk factor frequencies within candidate sub-types, defined for example by histology or by distinct tumor markers of interest. Increasingly tumors are being profiled for molecular features much more extensively. This greatly expands the opportunities for defining distinct sub-types. In this article we describe an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.