Article
Comparative microRNA expression profiles of cynomolgus monkeys, rat, and human reveal that mir-182 is involved in T2D pathogenic processes.
Journal of diabetes research - 1 Jan 2014
Zhou Jinghui, Meng Yuhuan, Tian Shuai, Chen Junhui, Liu Mingyu, Zhuo Min, Zhang Yu, Du Hongli, Wang Xiaoning
Abstract excerpt
Type 2 diabetes (T2D) is a prevalent disease that happens around the world and usually happens with insulin resistance. MicroRNAs (miRNAs) represented important roles in the suppression of gene expression and were proven to be related to human diseases. In this study, we used cynomolgus monkey fed with normal and high fatty diet (HFD), respectively, to analyze the miRNA expression profile in whole blood by deep...
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