Article
Identification of genomic signatures in circulating tumor cells from breast cancer.
International journal of cancer - 15 Jul 2015
Kanwar Nisha, Hu Pingzhao, Bedard Philippe, Clemons Mark, McCready David, Done Susan J
Abstract excerpt
Levels of circulating tumor cells (CTCs) in blood have prognostic value in early and metastatic breast cancer. CTCs also show varying degrees of concordance with molecular markers of primary tumors they originate from. It is expected that individual cells reflect the heterogeneity and evolution of tumor cells as they acquire new functions and differential responses to chemotherapy. However, a degree of...
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