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Article

Inhibition of nestin suppresses stem cell phenotype of glioblastomas through the alteration of post-translational modification of heat shock protein HSPA8/HSC71.

Cancer letters - 28 Feb 2015

Matsuda Yoko, Ishiwata Toshiyuki, Yoshimura Hisashi, Hagio Masahito, Arai Tomio

Abstract excerpt

Nestin, a class VI intermediate filament, was first described as a neuronal stem/progenitor cell marker. We previously reported that knockdown of nestin expression in human glioblastoma cells suppresses cell proliferation, migration, and invasion. In the present study, we examined the effect of n...

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Share to AC133 Antigen
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Share to HSC70 Heat-Shock Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25527454
DOI: 10.1016/j.canlet.2014.12.030

Genes

HSPA8
NANOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25527454-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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