Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2015

Kantorova Barbara, Malcikova Jitka, Smardova Jana, Pavlova Sarka, Trbusek Martin, Tom Nikola, Plevova Karla, Tichy Boris, Truong Sim, Diviskova Eva, Kotaskova Jana, Oltova Alexandra, Patten Nancy, Brychtova Yvona, Doubek Michael, Mayer Jiri, Pospisilova Sarka

Abstract excerpt

TP53 gene defects represent a strong adverse prognostic factor for patient survival and treatment resistance in chronic lymphocytic leukemia (CLL). Although various methods for TP53 mutation analysis have been reported, none of them allow the identification of all occurring sequence variants, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to High-Throughput Nucleotide Sequencing

Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25527155
DOI: 10.1007/s13277-014-2971-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25527155-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TP53 mutation analysis in chronic lymphocytic leukemia: comparison of different detection methods.PMID 25527155Read ↗

A comprehensive study of TP53 mutations in chronic lymphocytic leukemia: Analysis of 1287 diagnostic and 1148 follow-up CLL samples.Semantic proximity Read ↗

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update.Semantic proximity Read ↗

Detection of clinically relevant variants in the TP53 gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLLSemantic proximity Read ↗

Relevance of TP53 for CLL diagnosticsSemantic proximity Read ↗

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia—update on methodological approaches and results interpretationSemantic proximity Read ↗

ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia.Semantic proximity Read ↗

TP53 mutation and survival in chronic lymphocytic leukemia.Semantic proximity Read ↗

Low-burden TP53 mutations represent frequent genetic events in CLL with an increased risk for treatment initiation.Semantic proximity Read ↗

Landscape of TP53 Alterations in Chronic Lymphocytic Leukemia via Data Mining Mutation DatabasesSemantic proximity Read ↗

TP53 Mutations with Low Variant Allele Frequency Predict Short Survival in Chronic Lymphocytic Leukemia.Semantic proximity Read ↗

Denaturing high pressure liquid chromatography (DHPLC) for the analysis of somatic p53 mutations.Semantic proximity Read ↗

Five Percent Variant Allele Frequency Is a Reliable Reporting Threshold for TP53 Variants Detected by Next Generation Sequencing in Chronic Lymphocytic Leukemia in the Clinical SettingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.