Ginsenoside Re protects methamphetamine‐induced mitochondrial burdens and proapoptosis via genetic inhibition of protein kinase C δ in human neuroblastoma dopaminergic SH‐SY5Y cell lines

Abstract excerpt

Recently, we have demonstrated that ginsenoside Re protects methamphetamine (MA)-induced dopaminergic toxicity in mice via genetic inhibition of PKCδ and attenuation of mitochondrial stress. In addition, we have reported that induction of mitochondrial glutathione peroxidase (GPx) is also important for neuroprotection mediated by ginsenoside Re. To extend our knowledge, we examined the effects of ginsenoside Re...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biological and pharmacological studies of plants
• Share to Ginseng Biological Effects and Applications