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Article

Inhibition of autoimmune Chagas-like heart disease by bone marrow transplantation.

PLoS neglected tropical diseases - 1 Dec 2014

Guimaro Maria C, Alves Rozeneide M, Rose Ester, Sousa Alessandro O, de Cássia Rosa Ana, Hecht Mariana M, Sousa Marcelo V, Andrade Rafael R, Vital Tamires, Plachy Jiří, Nitz Nadjar, Hejnar Jiří, Gomes Clever C, L Teixeira Antonio R

Abstract excerpt

BACKGROUND: Infection with the protozoan Trypanosoma cruzi manifests in mammals as Chagas heart disease. The treatment available for chagasic cardiomyopathy is unsatisfactory. METHODS/PRINCIPAL FINDINGS: To study the disease pathology and its inhibition, we employed a syngeneic chicken model refractory to T. cruzi in which chickens hatched from T. cruzi inoculated eggs retained parasite kDNA (1.4 kb) minicircles....

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Identifiers

PMID: 25521296
DOI: 10.1371/journal.pntd.0003384
PMCID: PMC4270743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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