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Article

Determination of MICs of levofloxacin for Mycobacterium tuberculosis with gyrA mutations.

1 Oct 2015

Abstract excerpt

The purpose of the present study was to correlate gyrA mutations found in Mycobacterium tuberculosis isolates using the GenoType(®) MTBDRsl assay with minimum inhibitory concentrations of the fluoroquinolone levofloxacin (LVX). Of 123 archived clinical M. tuberculosis isolates evaluated, 93 isolates had an Ala90Val, Ser91Pro, Asp94Ala, Asn/Tyr, Gly or His mutation and 30 were wild-type. Phenotypically, gyrA...

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Identifiers

PMID: 25517815
DOI: 10.5588/ijtld.14.0277
PMCID: PMC4607084

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