Article
Correlating clinical breakpoint concentration of moxifloxacin with gyrA mutations using the GenoType MTBDRsl assay Version 2.0.
The Indian journal of tuberculosis - 1 Jul 2023
Sidiq Zeeshan, Hanif M, Dwivedi Kaushal Kumar, Chopra Kamal Kishore, Khanna Ashwani, Vashishat B K
Abstract excerpt
INTRODUCTION: Widespread use of Fluoroquinolones (FQs) has led to the development of its resistance in clinical isolates of Mycobacterium tuberculosis. However, in Mycobacterium tuberculosis, phenotypic resistance to FQs has been shown to be heterogeneous, ranging from low-level resistance to high-level resistance. This stratification in resistance has important implications for the inclusion of moxifloxacin...
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