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Article

HIF-1α (1772C>T) polymorphism as marker for breast cancer development.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2015

Meka Phanni Bhushann, Cingeetham Anuradha, Nanchari Santhoshi Rani, Damineni Surekha, Tipirisetti Nageshwarao, Gorre Manjula, Jarjapu Sarika, Annamaneni Sandhya, Digumarthi Raghunadharao, Satti Vishnupriya

Abstract excerpt

Hypoxia-inducible factor 1α (HIF-1α) is an important transcription factor that regulates different cellular responses to hypoxia. HIF-1α is rapidly degraded by von Hippel-Lindau (VHL) protein under normoxic conditions and stabilized under hypoxia. A common variant of HIF-1α (1772C>T) (rs 11549465) polymorphism, corresponding to an amino acid change from proline to serine at 582 position within the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

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Identifiers

PMID: 25510668
DOI: 10.1007/s13277-014-2949-y

Genes

VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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