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Article

Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective.

Drug and alcohol dependence - 1 Jun 2012

Vanyukov Michael M, Tarter Ralph E, Kirillova Galina P, Kirisci Levent, Reynolds Maureen D, Kreek Mary Jeanne, Conway Kevin P, Maher Brion S, Iacono William G, Bierut Laura, Neale Michael C, Clark Duncan B, Ridenour Ty A

Abstract excerpt

BACKGROUND: Two competing concepts address the development of involvement with psychoactive substances: the "gateway hypothesis" (GH) and common liability to addiction (CLA). METHOD: The literature on theoretical foundations and empirical findings related to both concepts is reviewed. RESULTS: The data suggest that drug use initiation sequencing, the core GH element, is variable and opportunistic rather than...

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Identifiers

PMID: 22261179
DOI: 10.1016/j.drugalcdep.2011.12.018
PMCID: PMC3600369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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