Article
Sequence variation and molecular evolution of BMP4 genes.
Genetics and molecular research : GMR - 7 Nov 2014
Zhang D J, Wu J H, Husile G, Sun H L, Zhang W G
Abstract excerpt
Bone morphogenetic protein 4 (BMP4) regulates skeletogenesis, osteoblastic differentiation, and the induction of hair follicles. Its protein-coding region contains a signal peptide, prodomain (which regulates post-translational synthesis), and a mature domain (which mediates gene function). Previous studies considered this gene to be conserved. By reanalyzing the coding region of BMP4 in 16 mammalian species, we...
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