Article
Polymorphisms in toll-like receptor 1 and 9 genes and their association with tuberculosis susceptibility in Chinese Holstein cattle.
Veterinary immunology and immunopathology - 30 Jun 2012
Sun Liping, Song Yapan, Riaz Hasan, Yang Hongzhen, Hua Guohua, Guo Aizhen, Yang Liguo
Abstract excerpt
Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a pivotal role in the innate and adaptive immune systems. Studies have shown that TLR variants play roles in various human infectious diseases. The aim of the present study was to investigate whether the functional genetic variations at positions C632T, G1409A, A1475C, G1550A and G1596A in TLR1 and at A2700G and A3156G in TLR9...
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