Article
Improved prediction of inhibitor development in previously untreated patients with severe haemophilia A.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2015
Hashemi S M, Fischer K, Moons K G M, van den Berg H M
Abstract excerpt
Treatment of previously untreated patients (PUPs) with severe haemophilia A is complicated by the formation of inhibitors. Prediction of PUPs with high risk is important to allow altering treatment with the intention to reduce the occurrence of inhibitors. An unselected multicentre cohort of 825 PUPs with severe haemophilia A (FVIII<0.01 IU mL(-1) ) was used. Patients were followed until 50 exposure days (EDs) or...
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