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Article

Receptor tyrosine kinase profiles and human papillomavirus status in oropharyngeal squamous cell carcinoma.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Oct 2015

Cortelazzi Barbara, Verderio Paolo, Ciniselli Chiara Maura, Pizzamiglio Sara, Bossi Paolo, Gloghini Annunziata, Gualeni Ambra V, Volpi Chiara C, Locati Laura, Pierotti Marco A, Licitra Lisa, Pilotti Silvana, Perrone Federica

Abstract excerpt

BACKGROUND: Human papillomavirus (HPV)-positive and HPV-negative oropharyngeal squamous cell carcinomas (OSCCs) are two distinct entities. We defined the molecular profiles of druggable receptor tyrosine kinases (RTKs) in both groups. MATERIALS AND METHODS: E5 expression and RTK alterations were studied in 17 HPV-positive and 59 HPV-negative formalin-fixed OSCCs. RTK activation was explored in further 12 frozen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25495427
DOI: 10.1111/jop.12301

Genes

EGFR
PTEN
IGF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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