Article
Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling
13 May 2008
Abstract excerpt
Uveal (ocular) melanoma is a highly aggressive cancer that leads to metastatic death in up to half of patients despite successful local therapy. Biomarkers of metastatic risk are critically needed to institute new adjuvant treatment strategies in high-risk patients. Previously, we showed that two prognostically significant molecular subtypes of uveal melanoma could be identified based on gene expression profiling...
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