Article
Non-coding RNAs in BRAF-mutant melanoma: targets, indicators, and therapeutic potential.
Naunyn-Schmiedeberg's archives of pharmacology - 1 Jan 2025
Afsar S, Syed Rahamat Unissa, Khojali Weam M A, Masood Najat, Osman Mhdia Elhadi, Jyothi J Siva, Hadi Mohd Abdul, Khalifa Amna Abakar Suleiman, Aboshouk Nayla Ahmed Mohammed, Alsaikhan Hessa Ahmed, Alafnan Aljuri Saleh, Alrashidi Bushra Abdullah
Abstract excerpt
Melanoma, a highly aggressive skin cancer, is often driven by BRAF mutations, such as the V600E mutation, which promotes cancer growth through the MAPK pathway and contributes to treatment resistance. Understanding the role of non-coding RNAs (ncRNAs) in these processes is crucial for developing new therapeutic strategies. This review aims to elucidate the relationship between ncRNAs and BRAF mutations in...
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