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Genetic Susceptibility to Chronic Kidney Disease – Some More Pieces for the Heritability Puzzle

31 May 2019

Abstract excerpt

Chronic kidney disease (CKD) is a major global health problem with an increasing prevalence partly driven by ageing population structure. Both genomic and environmental factors contribute to this complex heterogeneous disease. CKD heritability is estimated to be high (30-75%). Genome-wide association studies (GWAS) and GWAS meta-analyses have identified several genetic loci associated with CKD, including variants...

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PMID: 31214239
DOI: 10.3389/fgene.2019.00453

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