Article
Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials.
Head & neck - 1 Apr 2016
Dillon Patrick M, Chakraborty Samhita, Moskaluk Christopher A, Joshi Prashant J, Thomas Christopher Y
Abstract excerpt
BACKGROUND: Adenoid cystic carcinoma (ACC) is a rare tumor of secretory glands. In this study, recent advances in molecular characterization and in therapeutics are reviewed. METHODS: A search of articles in PubMed and of abstracts from national meetings was performed regarding ACC. RESULTS: Recent genetic analyses found that recurrent chromosome 6:9 translocations in ACC generate an MYB:NFIB gene fusion...
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