Article
Diversity of clinical implication of B-cell translocation gene 1 expression by histopathologic and anatomic subtypes of gastric cancer.
Digestive diseases and sciences - 1 May 2015
Kanda Mitsuro, Oya Hisaharu, Nomoto Shuji, Takami Hideki, Shimizu Dai, Hashimoto Ryoji, Sueoka Satoshi, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro
Abstract excerpt
BACKGROUND: Genetic signatures may differ by histopathologic and anatomic subtypes of gastric cancer (GC). B-cell translocation gene 1 (BTG1) was identified as one of genes downregulated in GC tissues from our microarray data. AIMS: To evaluate the clinical implications of BTG1 expression in GC and the genetic diversity among GC subtypes. METHODS: BTG1 mRNA expression was analyzed in GC cell lines and 233 pairs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.