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Article

The roles of BTG3 expression in gastric cancer: a potential marker for carcinogenesis and a target molecule for gene therapy.

Oncotarget - 14 Aug 2015

Gou Wen-feng, Yang Xue-feng, Shen Dao-fu, Zhao Shuang, Liu Yun-peng, Sun Hong-zhi, Takano Yasuo, Su Rong-jian, Luo Jun-sheng, Zheng Hua-chuan

Abstract excerpt

BTG (B-cell translocation gene) can inhibit cell proliferation, metastasis and angiogenesis, cell cycle progression, and induce differentiation in various cells. Here, we found that BTG3 overexpression inhibited proliferation, induced S/G2 arrest, differentiation, autophagy, apoptosis, suppressed migration and invasion in MKN28 and MGC803 cells (p < 0.05). BTG3 transfectants showed a higher mRNA expression of...

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Source

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Identifiers

PMID: 25904053
DOI: 10.18632/oncotarget.3734
PMCID: PMC4637325

Genes

BTG3
CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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