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T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.

Scientific reports - 8 Dec 2014

Ghassibe-Sabbagh Michella, Haber Marc, Salloum Angelique K, Al-Sarraj Yasser, Akle Yasmine, Hirbli Kamal, Romanos Jihane, Mouzaya Francis, Gauguier Dominique, Platt Daniel E, El-Shanti Hatem, Zalloua Pierre A

Abstract excerpt

Genome-wide association studies (GWAS) of multiple populations with distinctive genetic and lifestyle backgrounds are crucial to the understanding of Type 2 Diabetes Mellitus (T2DM) pathophysiology. We report a GWAS on the genetic basis of T2DM in a 3,286 Lebanese participants. More than 5,000,000 SNPs were directly genotyped or imputed using the 1000 Genomes Project reference panels. We identify genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25483131
DOI: 10.1038/srep07351
PMCID: PMC5376673

Genes

CDKAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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