Article
Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Tunisian Arab subjects.
Gene - 25 Jan 2013
Turki Amira, Al-Zaben Ghadeer S, Mtiraoui Nabil, Marmmuoch Hela, Mahjoub Touhami, Almawi Wassim Y
Abstract excerpt
Genome-wide association studies validated transcription factor 7-like 2 (TCF7L2) gene as confirmed type 2 diabetes (T2DM) susceptibility locus, and an ethnic contribution of TCF7L2 variants to T2DM risk was indicated. The aim of this study was to replicate in a Tunisian Arab population identified associations of common TCF7L2 variants with T2DM. We tested the association of TCF7L2 variants: rs4506565, rs7903146,...
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