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Article

Factors influencing ovulation and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.

International journal of cancer - 1 Sept 2015

Kotsopoulos Joanne, Lubinski Jan, Gronwald Jacek, Cybulski Cezary, Demsky Rochelle, Neuhausen Susan L, Kim-Sing Charmaine, Tung Nadine, Friedman Susan, Senter Leigha, Weitzel Jeffrey, Karlan Beth, Moller Pal, Sun Ping, Narod Steven A

Abstract excerpt

The role of the lifetime number of ovulatory cycles has not been evaluated in the context of BRCA-associated ovarian cancer. Thus, we conducted a matched case-control study to evaluate the relationship between the cumulative number of ovulatory cycles (and contributing components) and risk of developing ovarian cancer in BRCA mutation carriers (1,329 cases and 5,267 controls). Information regarding reproductive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25482078
DOI: 10.1002/ijc.29386
PMCID: PMC4458227

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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