Article
Breastfeeding and the risk of epithelial ovarian cancer among women with a BRCA1 or BRCA2 mutation.
Gynecologic oncology - 1 Dec 2020
Kotsopoulos Joanne, Gronwald Jacek, McCuaig Jeanna M, Karlan Beth Y, Eisen Andrea, Tung Nadine, Bordeleau Louise, Senter Leigha, Eng Charis, Couch Fergus, Fruscio Robert, Weitzel Jeffrey N, Olopade Olufunmilayo, Singer Christian F, Pal Tuya, Foulkes William D, Neuhausen Susan L, Sun Ping, Lubinski Jan, Narod Steven A
Abstract excerpt
OBJECTIVE: BRCA mutation carriers face a high lifetime risk of developing ovarian cancer. The strong inverse association between breastfeeding and the risk of ovarian cancer is established in the general population but is less well studied among women with a germline BRCA1 or BRCA2 mutation. METHOD: Thus, we conducted a matched case-control analysis to evaluate the association between breastfeeding history and...
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