Article
BAP1 and BRAFV600E expression in benign and malignant melanocytic proliferations.
Human pathology - 1 Feb 2015
Piris Adriano, Mihm Martin C, Hoang Mai P
Abstract excerpt
BAP1 (BRCA1-associated protein 1) is a tumor suppressor gene whose mutations have recently been reported to increase susceptibility for the development of uveal melanoma, cutaneous atypical and epithelioid melanocytic lesions, clear cell renal cell carcinoma, and other tumors. Screening for BAP1 mutation/loss/inactivation and BRAFV600E mutation can be done by immunohistochemistry. We investigated BAP1 and...
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