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Article

Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis

18 Nov 2014

Abstract excerpt

OBJECTIVE: We report the first pediatric specific Phenome-Wide Association Study (PheWAS) using electronic medical records (EMRs). Given the early success of PheWAS in adult populations, we investigated the feasibility of this approach in pediatric cohorts in which associations between a previously known genetic variant and a wide range of clinical or physiological traits were evaluated. Although computationally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25477900
DOI: 10.3389/fgene.2014.00401

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