Article
PIK3CA mutations in Peruvian patients with HER2-amplified and triple negative non-metastatic breast cancers.
Hematology/oncology and stem cell therapy - 1 Dec 2014
Castaneda Carlos A, Lopez-Ilasaca Marco, Pinto Joseph A, Chirinos-Arias Michelle, Doimi Franco, Neciosup Silvia P, Rojas Katerin I, Vidaurre Tatiana, Balko Justin M, Arteaga Carlos L, Gomez Henry L
Abstract excerpt
PURPOSE: To determine the frequency of PIK3CA mutations in a Peruvian cohort with HER2-amplified and triple negative breast cancers (TNBC). METHODS: We analyzed two cohorts of 134 primary non-metastatic breast cancer patients from Peru. Cohorts consisted of 51 hormone receptors (+)/HER2-amplified breast tumor patients surgically resected as first treatment included in the ALTTO trial (ALTTO cohort) and 81 TNBC...
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