Biologically active compounds based on the privileged 2-imidazoline scaffold: The world beyond adrenergic/imidazoline receptor modulators.

Abstract excerpt

2-Imidazolines are well known as pharmacophores for various isoforms of adrenergic (α) and imidazoline (I) receptors. The biological activities exerted through the modulation of these targets, mostly in the central nervous system, have found utility in the development of many drug candidates - and even marketed drugs - for hypertension, diabetes and various CNS disorders. However, there is a growing evidence for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drug Discovery
• Share to Imidazoles
• Share to Molecular Targeted Therapy