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Article

Genome-wide association studies in nephrology: using known associations for data checks.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Feb 2015

Wuttke Matthias, Schaefer Franz, Wong Craig S, Köttgen Anna

Abstract excerpt

Prior to conducting genome-wide association studies (GWAS) of renal traits and diseases, systematic checks to ensure data integrity and analytical work flow should be conducted. Using positive controls (ie, known associations between a single-nucleotide polymorphism [SNP] and a corresponding trait) allows for identifying errors that are not apparent solely from global evaluation of summary statistics. Strong...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25465167
DOI: 10.1053/j.ajkd.2014.09.019
PMCID: PMC4305458

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CST3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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