Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium.

doi:10.1093/ndt/gfv342

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Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Feb 2016

Wuttke Matthias, Wong Craig S, Wühl Elke, Epting Daniel, Luo Li, Hoppmann Anselm, Doyon Anke, Li Yong, Sözeri Betül, Thurn Daniela, Helmstädter Martin, Huber Tobias B, Blydt-Hansen Tom D, Kramer-Zucker Albrecht, Mehls Otto, Melk Anette, Querfeld Uwe, Furth Susan L, Warady Bradley A, Schaefer Franz, Köttgen Anna

Abstract excerpt

BACKGROUND: Chronic kidney disease (CKD) in children is characterized by rapid progression and a high incidence of end-stage renal disease and therefore constitutes an important health problem. While unbiased genetic screens have identified common risk variants influencing renal function and CKD in adults, the presence and identity of such variants in pediatric CKD are unknown. METHODS: The international...

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PMID: 26420894
DOI: 10.1093/ndt/gfv342
PMCID: PMC4829056

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