Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population.

The Journal of urology - 1 May 2015

Choudhry Shweta, Baskin Laurence S, Lammer Edward J, Witte John S, Dasgupta Sudeshna, Ma Chen, Surampalli Abhilasha, Shen Joel, Shaw Gary M, Carmichael Suzan L

Abstract excerpt

PURPOSE: Estrogenic endocrine disruptors acting via estrogen receptors α (ESR1) and β (ESR2) have been implicated in the etiology of hypospadias, a common congenital malformation of the male external genitalia. We determined the association of single nucleotide polymorphisms in ESR1 and ESR2 genes with hypospadias in a racially/ethnically diverse study population of California births. MATERIALS AND METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to California
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

Share to Estrogen Receptor beta

Share to Hypospadias

Share to Infant, Newborn

Share to Racial Groups

Source

Identifiers

PMID: 25463985
DOI: 10.1016/j.juro.2014.11.087

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population.PMID 25463985Read ↗

Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias.Semantic proximity Read ↗

Polymorphisms of estrogen receptor beta gene are associated with hypospadias.Semantic proximity Read ↗

[Gene polymorphisms of estrogen receptor α correlated with hypospadias in children].Semantic proximity Read ↗

Risk factors for hypospadias in the estrogen receptor 2 gene.Semantic proximity Read ↗

Genetics of hypospadias: are single-nucleotide polymorphisms in SRD5A2, ESR1, ESR2, and ATF3 really associated with the malformation?Semantic proximity Read ↗

Multilocus analyses of estrogen-related genes reveal involvement of the ESR1 gene in male infertility and the polygenic nature of the pathology.Semantic proximity Read ↗

Biallelic and monoallelic ESR2 variants associated with 46,XY disorders of sex development.Semantic proximity Read ↗

Mutations and polymorphisms of estrogens receptors genes and diseases susceptibility.Semantic proximity Read ↗

Molecular epidemiology of hypospadias: review of genetic and environmental risk factors.Semantic proximity Read ↗

Environmental and genetic contributors to hypospadias: a review of the epidemiologic evidence.Semantic proximity Read ↗

Hypospadias and variants in genes related to sex hormone biosynthesis and metabolism.Semantic proximity Read ↗

Haplotype analysis of the estrogen receptor 1 gene in male genital and reproductive abnormalities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.