Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

De novo FUS mutations in 2 Korean patients with sporadic amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Mar 2015

Kim Young-Eun, Oh Ki-Wook, Kwon Min-Jung, Choi Won-Jun, Oh Seong-il, Ki Chang-Seok, Kim Seung Hyun

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder. Approximately 5% of ALS patients are familial (fALS) cases, and the remaining 95% are apparently sporadic (sALS) cases. To date, a number of genes have been discovered as associated with ALS, but the genetic background of sALS is not yet fully understood. The occurrence of de novo mutations in ALS genes might be an explanation for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Genetic Association Studies

Share to RNA-Binding Protein FUS

Share to Young Adult

Source

Identifiers

PMID: 25457557
DOI: 10.1016/j.neurobiolaging.2014.10.002

Genes

FUS
SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

De novo FUS mutations in 2 Korean patients with sporadic amyotrophic lateral sclerosis.PMID 25457557Read ↗

De novo FUS gene mutations are associated with juvenile-onset sporadic amyotrophic lateral sclerosis in China.Semantic proximity Read ↗

Novel Pathogenic Variants Leading to Sporadic Amyotrophic Lateral Sclerosis in Greek Patients.Semantic proximity Read ↗

Identification of novel FUS mutations in sporadic cases of amyotrophic lateral sclerosis.Semantic proximity Read ↗

Novel and Recurrent Mutations in a Cohort of Chinese Patients With Young-Onset Amyotrophic Lateral SclerosisSemantic proximity Read ↗

De novo nonsense mutation of the FUS gene in an apparently familial amyotrophic lateral sclerosis case.Semantic proximity Read ↗

Novel FUS mutations identified through molecular screening in a large cohort of familial and sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

Screening of the FUS gene in familial and sporadic amyotrophic lateral sclerosis patients of Chinese origin.Semantic proximity Read ↗

Novel FUS mutation Y526F causing rapidly progressive familial amyotrophic lateral sclerosis.Semantic proximity Read ↗

Screening of the SOD1, FUS, TARDBP, ANG, and OPTN mutations in Korean patients with familial and sporadic ALS.Semantic proximity Read ↗

FUS-associated ALS in Taiwan: genetic spectrum, clinical features, and a founder haplotype of p.H517D.Semantic proximity Read ↗

Fus gene mutations in familial and sporadic amyotrophic lateral sclerosis.Semantic proximity Read ↗

Mutations in FUS cause FALS and SALS in French and French Canadian populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.