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Article

Effects of the nuclear localization of the N(pro) protein of classical swine fever virus on its virulence in pigs.

Veterinary microbiology - 5 Dec 2014

Li Yongfeng, Shen Liang, Sun Yuan, Wang Xiao, Li Chao, Huang Junhua, Chen Jianing, Li Lianfeng, Zhao Bibo, Luo Yuzi, Li Su, Qiu Hua-Ji

Abstract excerpt

The N(pro) protein of classical swine fever virus (CSFV) is localized in the cytoplasm and nucleus. However, it is unknown whether the nuclear localization of N(pro) correlates with the virulence of CSFV in the host. Previously, we showed that the N(pro) protein fused with interferon regulatory factor 3 (IRF3) was present only in the cytoplasm. Here, we generated and evaluated a recombinant CSFV vSM-IRF3...

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Identifiers

PMID: 25457365
DOI: 10.1016/j.vetmic.2014.09.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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