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Article

Functional mapping of the porcine reproductive and respiratory syndrome virus capsid protein nuclear localization signal and its pathogenic association.

Virus research - 1 Jul 2008

Pei Yanlong, Hodgins Douglas C, Lee Changhee, Calvert Jay G, Welch Siao-Kun W, Jolie Rika, Keith Marcia, Yoo Dongwan

Abstract excerpt

PRRSV (porcine reproductive and respiratory syndrome virus) nucleocapsid (N) protein is the most abundant structural protein of the virus. During infection, the N protein is specifically localized to the nucleus and nucleolus in addition to its normal cytoplasmic distribution. Previously, a nuclear localization signal (NLS, 41-PGKK(N/S)KKKN)-null mutant virus (41-PGGGNKKKN) showed reduced viremia and increased...

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Identifiers

PMID: 18403041
DOI: 10.1016/j.virusres.2008.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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