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Article

N(pro) of classical swine fever virus prevents type I interferon-mediated priming of conventional dendritic cells for enhanced interferon-α response.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 May 2012

Hüsser Linda, Ruggli Nicolas, Summerfield Artur

Abstract excerpt

A hallmark of acute classical swine fever is the high interferon (IFN)-α levels found in the serum early after infection, followed by an inflammatory cytokine storm. Plasmacytoid dendritic cells (pDCs) represent the only known cell type that produces IFN-α upon classical swine fever virus (CSFV)...

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Identifiers

PMID: 22313263
DOI: 10.1089/jir.2011.0068

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22313263-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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