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Article

Topographical cues regulate the crosstalk between MSCs and macrophages.

Biomaterials - 1 Jan 2015

Vallés Gema, Bensiamar Fátima, Crespo Lara, Arruebo Manuel, Vilaboa Nuria, Saldaña Laura

Abstract excerpt

Implantation of scaffolds may elicit a host foreign body response triggered by monocyte/macrophage lineage cells. Growing evidence suggests that topographical cues of scaffolds play an important role in MSC functionality. In this work, we examined whether surface topographical features can regulate paracrine interactions that MSCs establish with macrophages. Three-dimensional (3D) topography sensing drives MSCs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25453943
DOI: 10.1016/j.biomaterials.2014.10.028
PMCID: PMC4245715

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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