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Maternal pregnancy-related infections and autism spectrum disorder-the genetic perspective.

Translational psychiatry - 16 Aug 2022

Nudel Ron, Thompson Wesley K, Børglum Anders D, Hougaard David M, Mortensen Preben B, Werge Thomas, Nordentoft Merete, Benros Michael E

Abstract excerpt

Autism spectrum disorder (ASD) refers to a group of neurodevelopmental disorders which include deficits in behavior, social interaction and communication. ASD has a complex genetic architecture, and it is also influenced by certain environmental exposures. Both types of predisposing factors may be related to immunological mechanisms, involving, for example, immune system genes and infections. Past studies have...

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Identifiers

PMID: 35974006
DOI: 10.1038/s41398-022-02068-9
PMCID: PMC9381559

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