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Article

Circulating cell free DNA testing: are some test failures informative?

2 Dec 2014

Abstract excerpt

OBJECTIVE: The proportion of circulating cell free DNA derived from the feto-placental unit (fetal fraction or FF) correlates with test success and interpretation reliability. Some fetal disorders are associated with systematically lower FF, sometimes resulting in noninformative results. METHODS: We analyzed results from pregnancies tested in a nested case/control study derived from a cohort of 4664 high-risk...

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PMID: 25449554
DOI: 10.1002/pd.4541

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